Yong-Su Jin

• Quantitative microbial physiology at both molecular and systems levels

• Metabolic engineering for production of value added products (fuels, chemicals, and nutraceuticals)

Dr. Jin's research focuses on discovery and understanding of genetic and environmental perturbations which elicit beneficial phenotypes of microorganism through systems and synthetic approaches. Specifically, Dr. Jin is working on elucidating relationships between genotype and phenotypes in the context of value-added biotransformation (fuels and chemicals) and stress tolerance (solvents, nanomaterials, and antibiotics).

Dr. Jin's Lab Website:  http://jin.openwetware.org/

Selected publications

Lee, J., Seo, E., Kweon, D.H., Park, K., Jin, Y.S. Fermentation of rice bran and defatted rice rran for butanol production using Clostridium beijerinckii NCIMB 8052. Journal of Microbiology and Biotechnology 19, 482-490 (2009).

Hong, M.E., Lee, K.S., Yu, B.J., Sung, Y.J., Park, S.M., Koo, H.M., Kweon, D.H., Park, J.C., Jin, Y.S. Identification of gene targets eliciting improved alcohol tolerance in Saccharomyces cerevisiae through inverse metabolic engineering. Journal of Biotechnology 149, 52-59 (2010).

Jung, S.C., Smith, C.L., Lee, K.S., Hong, M.E., Kweon, D.H., Stephanopoulos, G., Jin, Y.S. Restoration of growth phenotypes of Escherichia coli DH5alpha in minimal media through reversal of a point mutation in purB. Applied and Environmental Microbiology 76, 6307-6309 (2010).

Kim, S.R., Lee, K.S., Choi, J.H., Ha, S.J., Kweon, D.H., Seo, J.H., Jin, Y.S. Repeated-batch fermentations of xylose and glucose-xylose mixtures using a respiration-deficient Saccharomyces cerevisiae engineered for xylose metabolism. Journal of Biotechnology 150, 404-407 (2010).

Lee, K.S., Hong, M.E., Jung, S.C., Ha, S.J., Yu, B.J., Koo, H.M., Park, S.M., Seo, J.H., Kweon, D.H., Park, J.C., Jin, Y.S. Improved galactose fermentation of Saccharomyces cerevisiae through inverse metabolic engineering. Biotechnology and Bioengineering 108, 621-631 (2011).

Ha S.J., Galazka J.M., Rin Kim S., Choi J.H., Yang X., Seo J.H., Louise Glass N., Cate J.H., Jin Y.S. Engineered Saccharomyces cerevisiae capable of simultaneous cellobiose and xylose fermentation. Proceeding of the National Academy of Sciences 108, 504-509 (2011)

Courses recently taught:

FSHN 471/MCB 434 - Food and Industrial Microbiology

FSHN 472 - Sanitation of Food Processing

Ph. D. University of Wisconsin-Madison, 2002

Dr. Jin received his B.S. and M. S. in Food Science and Technology at Seoul National University 1996 and 1998, respectively. In 2002 he received Ph. D. degree in Food Science and Bacteriology (minor) at the University of Wisconsin-Madison under the advisement of Prof. Thomas Jeffries. After completing a post-doctoral training under the advisement of Prof. Gregory Stephanopoulos at Massachusetts Institute of Technology, he served as an Assistant Professor in the Department of Food Science and Biotechnology at Sungkyunkwan University in Korea from 2006 to 2008. In August of 2008, he joined the faculty of Food Science and Human Nutrition as an Assistant Professor in Microbial Genomics.